ARTEROLANE (PhEur)

Arterolane, also known as OZ277, is a pharmaceutical substance that is used in the treatment of malaria. Its CAS number is 664338-39-0. Arterolane belongs to the class of antimalarial drugs known as arylaminoalcohols. It works by inhibiting the growth and replication of the Plasmodium parasite responsible for causing malaria.

Arterolane is highly effective against both drug-sensitive and drug-resistant strains of Plasmodium falciparum, the most deadly species of malaria parasite. It is commonly used in combination therapy with another antimalarial drug called piperaquine to improve treatment outcomes and prevent the development of drug resistance.

Arterolane has a relatively short half-life in the body, allowing for once-daily dosing. It is generally well-tolerated, with mild and transient side effects such as headache, nausea, and dizziness being reported.

As an important tool in the fight against malaria, arterolane demonstrates promising results in clinical trials and is being utilized in various malar