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Lumefantrine, with CAS number 82186-77-4, is a pharmaceutical substance used primarily in the treatment of malaria. It is a synthetic antimalarial agent that belongs to the artemisinin-based combination therapy (ACT) class of drugs. Lumefantrine is commonly combined with another antimalarial drug called artemether to form a highly effective treatment for uncomplicated malaria caused by Plasmodium falciparum. Lumefantrine works by inhibiting the growth and replication of the malaria parasite within the red blood cells. It targets the parasite's mitochondrial electron transport chain, leading to disruption of its energy metabolism and ultimately causing its death. The drug is administered orally in tablet form and is generally well-tolerated, with a favorable safety profile. Due to the emergence of artemisinin resistance in some regions, lumefantrine has become an essential component in the fight against malaria. The combination therapy of lumefantrine and artemether has proven to be highly effective, providi -
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Luliconazole is a pharmaceutical substance commonly used as an antifungal agent. It is marketed under the brand name Lulicon and is categorized as an imidazole antifungal medication. Luliconazole is primarily used to treat certain fungal infections of the skin, including athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). The Chemical Abstracts Service (CAS) number for luliconazole is 187164-19-8. It is available in the form of a topical cream or solution that is applied directly to the affected area of the skin. Luliconazole works by inhibiting the growth of fungi and disrupting their cell membranes, ultimately killing the fungal cells. While generally well-tolerated, some common side effects of luliconazole may include skin irritation, redness, itching, or burning sensation at the application site. It is important to follow the instructions provided by a healthcare professional or the product labeling when using luliconazole to ensure proper application and dosing. Luli -
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Loteprednol is a pharmaceutical substance that belongs to the corticosteroid class of medications. Its CAS number is 129260-79-3. Loteprednol is commonly used for the treatment of various inflammatory eye conditions, such as postoperative inflammation, seasonal allergic conjunctivitis, and uveitis. Loteprednol works by inhibiting the production of inflammation-causing substances in the body, thereby reducing swelling, redness, and itching in the eyes. It is available in the form of eye drops and ointments, which are applied directly to the affected eye(s). This pharmaceutical substance has a relatively low risk of side effects compared to other corticosteroids. Common side effects may include temporary blurred vision, stinging or burning sensation upon application, and increased sensitivity to light. However, serious side effects such as eye infections or increased pressure in the eye may occur rarely but should be reported to a healthcare professional immediately. Loteprednol is typically prescribed by an -
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Lifitegrast is a pharmaceutical substance used in the treatment of dry eye disease. Its chemical name is 4-((1R)-2-(6-(2-methyl-1H-imidazol-1-yl)pyridin-2-yl)-1-pyrrolidinyl)-2-(trifluoromethyl)benzonitrile. The CAS number for Lifitegrast is 1025967-78-5. -
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Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce inflammation and relieve pain. Its chemical name is 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid. The CAS number for Indomethacin is 53-86-1. It works by inhibiting the production of prostaglandins, which are substances in the body that cause inflammation, pain, and fever. Indomethacin is commonly prescribed for conditions such as arthritis, gout, and menstrual pain. Indomethacin is available in various forms, including oral capsules, suppositories, and injections. The specific dosage and duration of treatment depend on the individual's condition and response to the medication. It is important to follow the prescribed dosage and instructions provided by a healthcare professional. While Indomethacin can be effective in reducing pain and inflammation, like other NSAIDs, it may also have potential side effects. Common side effects include stomach upset, nausea, dizziness, headache, and skin rash. It can also inc -
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Iguratimod, also known as T-614, is a pharmaceutical substance used for the treatment of rheumatoid arthritis and other autoimmune diseases. Its chemical name is 3-(2-[(4-methoxybenzoyl) amino] pyridine-4-carboxamido) phenylboronic acid. The CAS number for Iguratimod is 123663-49-0. -
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Hydroxychloroquine, also known by its CAS number 118-42-3, is a pharmaceutical substance primarily used to treat malaria, rheumatoid arthritis, and lupus erythematosus. It belongs to the class of medications known as antimalarials and is derived from the closely related drug chloroquine. Hydroxychloroquine works by interfering with the growth and reproduction of parasites, thereby preventing the spread of malaria within the body. Additionally, it exhibits immunomodulatory properties that help control autoimmune diseases like rheumatoid arthritis and lupus erythematosus. This pharmaceutical substance is available in oral tablet or suspension form, providing a safe and effective treatment option for various medical conditions. -
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Halofantrine, with CAS number 69756-53-2, is a pharmaceutical substance used for the treatment of malaria. It belongs to the class of antimalarial agents and is primarily used to treat infections caused by Plasmodium falciparum, which is a severe and potentially fatal form of malaria. Halofantrine is available in tablet form and is administered orally. It works by targeting the parasite's ability to reproduce and survive in the body. The substance interferes with the formation of hemozoin, a toxic byproduct of hemoglobin digestion by the parasites, leading to their death. While halofantrine has shown effectiveness in treating malaria, it is recommended to be used cautiously due to its potential side effects. Common side effects may include gastrointestinal discomfort, vomiting, and dizziness. It may also cause cardiac complications, such as QT prolongation, which can lead to abnormal heart rhythms. As with any pharmaceutical substance, it is important to carefully follow the prescribed dosage and duration -
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FLUOROMETHOLONE is a pharmaceutical substance used in the form of eye drops or ointment for the treatment of various eye conditions. It is a synthetic fluorinated corticosteroid that has anti-inflammatory and anti-allergic properties. Its CAS number is 426-13-1. FLUOROMETHOLONE works by reducing inflammation and swelling in the eyes, thereby relieving symptoms such as redness, itching, and discomfort. It is commonly prescribed for conditions such as conjunctivitis, allergic conjunctivitis, uveitis, and keratitis. However, it is important to use FLUOROMETHOLONE as directed and under the supervision of a healthcare professional to avoid possible side effects and complications. -
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Flucytosine, also known by its generic name 5-Fluorocytosine, is a pharmaceutical substance primarily used in the treatment of fungal infections, particularly those caused by Candida and Cryptococcus species. Its chemical structure consists of a cytosine base with a fluorine atom at the 5-position, hence its name. The Chemical Abstracts Service (CAS) number for Flucytosine is 2022-85-7. It is available in various dosage forms, including oral tablets and capsules. Flucytosine is an antifungal agent that works by inhibiting the synthesis of fungal DNA and RNA, thereby disrupting the growth and replication of the fungal cells. Upon oral administration, Flucytosine is readily absorbed into the bloodstream and widely distributed throughout the body. It undergoes enzymatic conversion by cytosine deaminase within the fungal cells into its active form, 5-fluorouracil. 5-fluorouracil functions by inhibiting thymidylate synthase, an essential enzyme for the synthesis of DNA. Flucytosine is frequently used in combina -
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Fenticonazole, also known by its CAS number 72479-26-6, is a pharmaceutical substance that belongs to the class of antifungal drugs. It is primarily used to treat various fungal infections, including dermatophytosis (ringworm), candidiasis (yeast infection), and pityriasis versicolor (a fungal skin infection). Fenticonazole works by inhibiting the growth and reproduction of fungus in the body. It does this by interfering with the synthesis of ergosterol, an essential component of the fungal cell membrane. Without ergosterol, the fungal cell membrane becomes leaky and weak, leading to the death of the fungus. This pharmaceutical substance is available in various formulations, such as creams, powders, solutions, and suppositories, allowing for different routes of administration depending on the type and location of the infection. It is typically applied topically or vaginally, and in some cases, it may be prescribed orally. Fenticonazole has shown efficacy in treating a wide range of fungal infections and is -
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Fenspiride is a pharmaceutical substance with the CAS number 5053-06-5. It is an anti-inflammatory and bronchodilator agent used in the treatment of respiratory conditions such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). Fenspiride acts by reducing inflammation in the airways, improving the flow of air, and relieving symptoms associated with respiratory disorders. It is available in oral tablet form and is commonly prescribed by healthcare professionals to manage and alleviate respiratory symptoms in patients. -
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The pharmaceutical substance Efinaconazole is an antifungal agent that is used for the treatment of fungal infections, particularly those affecting the nails (onychomycosis). It is available in the form of a topical solution or nail lacquer. Efinaconazole is chemically classified as an imidazole derivative and its chemical name is 2,4-dichloro-N-{(2R,3S)-1-[6-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)pyrimidin-4-yl]azetidin-3-yl}benzamide. The CAS (Chemical Abstracts Service) number of Efinaconazole is 164650-44-6. -
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Dimethyl fumarate is a pharmaceutical substance that is classified as an immunomodulatory agent. Its chemical name is dimethyl (2E)-but-2-enedioate, and its CAS number is 624-49-7. Dimethyl fumarate is commonly used as an oral treatment for multiple sclerosis (MS). It works by reducing inflammation and preventing damage to the myelin sheath, which is the protective covering of nerve fibers. By modulating the immune system, dimethyl fumarate helps to decrease the frequency and severity of MS relapses. In addition to its immunomodulatory properties, dimethyl fumarate is also known for its antioxidant effects. It can scavenge reactive oxygen species, which are harmful molecules that can cause cellular damage. This antioxidant activity may contribute to the neuroprotective benefits of dimethyl fumarate in MS treatment. Dimethyl fumarate is typically prescribed in the form of delayed-release capsules. The recommended dosage varies depending on the specific condition being treated, and it is usually taken twice -
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DIFLUPREDNATE is a pharmaceutical substance used in the treatment of eye inflammation. It is a corticosteroid and belongs to the class of anti-inflammatory medications. The CAS number of DIFLUPREDNATE is 23674-86-4. -
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Dexamethasone is a pharmaceutical substance that belongs to the class of corticosteroid drugs. It is known by its chemical name 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. The CAS number for dexamethasone is 50-02-2. Dexamethasone is a synthetic corticosteroid that has potent anti-inflammatory and immunosuppressive properties. It is commonly used in the treatment of various inflammatory conditions, allergies, and autoimmune disorders. Dexamethasone works by suppressing the immune system, reducing inflammation, and decreasing the release of substances in the body that cause inflammation. This pharmaceutical substance is available in various forms such as tablets, injections, eye drops, and creams. It is often prescribed by healthcare professionals for short-term use to control acute symptoms, or for long-term use in chronic conditions. Dexamethasone should be used under medical supervision, as it can have significant side effects and interactions with other medications. Some common -
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Desonide is a synthetic corticosteroid drug that is used topically for the treatment of various skin conditions, including eczema, dermatitis, and psoriasis. It is classified as a class 1 corticosteroid, which means it has the highest potency among topical corticosteroids. The chemical name of desonide is 11β,21-Dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione, and its CAS number is 638-94-8. Desonide works by reducing inflammation, itching, and redness associated with skin conditions. It is available in various forms such as creams, ointments, lotions, and gels. As with any corticosteroid, desonide should be used as directed by a healthcare professional and for the prescribed duration. Prolonged or excessive use may lead to systemic absorption and potential side effects, such as thinning of the skin, skin discoloration, or steroid acne. Desonide has been found to be effective in managing a wide range of skin conditions, providing relief to individuals suffering from discomfort and improvi -
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Cyclosporine is a pharmaceutical substance that is also known by its generic name, ciclosporin. Its chemical name is (E)-cyclo[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutanoyl-N-methylglycine. The CAS number for cyclosporine is 59865-13-3. Cyclosporine is primarily used as an immunosuppressant drug. It works by suppressing the immune system to prevent rejection of transplanted organs. It is commonly prescribed to organ transplant patients to help prevent their bodies from rejecting the new organ. Additionally, cyclosporine is used to treat certain autoimmune disorders like psoriasis, rheumatoid arthritis, and a severe form of dry eye disease called keratoconjunctivitis sicca. In these conditions, cyclosporine helps to reduce inflammation and improve symptoms. Cyclosporine is available in various forms such as capsules, oral solution, and injection, depending on the specific treatment requirements. It is typically administered under the supervision of a healthcare professional due -
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Cycloguanil pamoate is a pharmaceutical substance that belongs to the class of antimalarial drugs. Its chemical name is 4,6-diamino-N-(2,5-dimethoxyphenyl)-1,3,5-triazin-2-amine pamoate. The CAS number of Cycloguanil pamoate is 609-78-9. Cycloguanil pamoate is used in the treatment and prevention of malaria caused by Plasmodium falciparum, a parasite transmitted through the bite of infected mosquitoes. It works by inhibiting the replication of the parasite, ultimately reducing the symptoms and preventing further transmission of the disease. This pharmaceutical substance is typically administered orally or intravenously. Common side effects may include nausea, vomiting, diarrhea, headache, and dizziness. It is important to follow the prescribed dosage and complete the entire course of treatment to ensure effectiveness. Overall, Cycloguanil pamoate is an essential component in the fight against malaria, a life-threatening disease that impacts millions of people worldwide. -
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CRISABOROLE is a pharmaceutical substance with the CAS number 906673-24-3. It is an ointment that is used topically for the treatment of mild-to-moderate atopic dermatitis (eczema) in patients aged 2 years and older. CRISABOROLE belongs to a class of medications called phosphodiesterase 4 (PDE4) inhibitors. It works by inhibiting the enzyme PDE4, which reduces inflammation and itching associated with atopic dermatitis. This drug is believed to have both anti-inflammatory and anti-itch properties. The ointment is typically applied directly to the affected skin twice daily. It is important to follow the instructions provided by a healthcare professional and to avoid using this medication on broken or infected skin. Common side effects of CRISABOROLE may include burning or stinging sensation at the application site, as well as skin redness or irritation. As with any medication, it is important to consult a healthcare professional before using CRISABOROLE to determine if it is suitable for individual circumsta -
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Chloroquine, also known by its CAS number 54-05-7, is a pharmaceutical substance primarily used for its antimalarial properties. It belongs to the class of 4-aminoquinoline compounds and is widely used in the prevention and treatment of malaria, caused by Plasmodium species. This pharmaceutical substance works by interfering with the growth and reproduction of the parasites in the red blood cells. Chloroquine inhibits heme polymerase enzyme, resulting in the accumulation of toxic heme metabolites within the parasites. This accumulation ultimately leads to the death of the parasites, thereby reducing the severity and duration of malarial infections. In addition to its antimalarial effects, chloroquine also exhibits immunomodulatory and anti-inflammatory properties. It has been used to treat certain autoimmune diseases, such as rheumatoid arthritis and lupus erythematosus, by reducing the production and release of pro-inflammatory cytokines. Chloroquine is available in various formulations, including tablets -
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Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) used as a potent and selective inhibitor of cyclooxygenase-2 (COX-2). Its chemical name is 2-amino-3-(4-bromobenzoyl)phenylacetic acid, and it has the CAS number 91714-94-2. Bromfenac is primarily used as an ophthalmic solution to treat inflammation and pain following cataract surgery. It works by inhibiting the production of prostaglandins, which are inflammatory mediators involved in the development of pain, swelling, and redness. By blocking the action of COX-2, bromfenac helps reduce these post-operative symptoms and improve patient comfort. The ophthalmic solution of bromfenac is available in different strengths and is typically applied topically to the affected eye(s) in the form of eye drops. It is administered by healthcare professionals or as directed by a physician. The solution is usually well-tolerated, with the common side effects being temporary burning or stinging sensation upon application. Bromfenac is known for its high potency an -
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BREMELANOTIDE is a pharmaceutical substance primarily used for the treatment of female sexual dysfunction. Its chemical name is "Ac-Nle-c[Asp-His-(D-Phe)-Arg-Trp-Lys]-OH" and its CAS number is 189691-06-3. BREMELANOTIDE is a synthetic peptide that acts as a melanocortin receptor agonist. It specifically targets the melanocortin receptor 4 (MC4R), which is involved in regulating sexual arousal and desire in the brain. By activating the MC4R, BREMELANOTIDE enhances sexual desire and arousal in women, particularly those with hypoactive sexual desire disorder. This pharmaceutical substance is typically administered as a subcutaneous injection. It is currently under development and evaluation for its safety and efficacy in treating female sexual dysfunction. BREMELANOTIDE has shown promising results in clinical trials, with improved sexual desire and satisfaction reported among the patients. However, it is important to note that as with any pharmaceutical substance, BREMELANOTIDE may have potential side effects -
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Betaxolol is a pharmaceutical substance that belongs to the class of beta-adrenergic blocking agents. Its systematic name is (RS)-1-[4-(2-Isopropoxyethoxymethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol. The CAS number for Betaxolol is 63659-18-7. It is mainly used to treat high blood pressure (hypertension) and certain heart conditions, such as angina and arrhythmias. Betaxolol works by blocking the action of certain natural chemicals in the body, such as adrenaline, that can increase heart rate and blood pressure. It is available in various forms such as tablets and eye drops. When prescribed as eye drops, Betaxolol is commonly used to reduce intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It helps to decrease the production of aqueous humor, reducing the pressure in the eye and preventing damage to the optic nerve. Betaxolol is typically administered under medical supervision, and the dosage may vary depending on the specific condition being treated. Common side eff
